Her research is currently focused on the ecology and evolution of multi-drug resistance (MDR) plasmids in bacteria. Since rapid spread of MDR to human pathogens threatens the treatment of infectious diseases, novel therapies are needed that limit the spread of new resistance genes. However, the factors that determine successful transfer and persistence of MDR plasmids are still poorly understood. Her main research questions focus on the evolutionary mechanisms and dynamics of plasmid-bacteria co-evolution. She is also interested in the natural reservoirs, diversity and evolutionary history of MDR plasmids in environmental habitats, and studies the effects of spreading dairy manure on the abundance and diversity of MDR plasmid reservoirs in soils.